bronchoscope
Conditions
Interventions
control group:Propofol
experimental group:Cyclopofol
Sponsors
Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo fiberoptic bronchoscopy; 2. Plan to use non-intubated general anesthesia; 3. Gender is not limited, age >= 18 and = 90%; systolic blood pressure >= 90 mmHg; DBP >= 55 mmHg; HR 50-100 times/min; 6. The American Society of Anesthesiologists (ASA) grades I to III; 7. Able to understand the procedures and methods of this trial, willing to strictly abide by the clinical research protocol to complete this trial, and voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who have anesthesia/sedation contraindications or have had anesthesia/sedation accidents in the past; 2. People who are known to be allergic to eggs, soy products, opioids and their rescue drugs, propofol, etc.; those with contraindications to propofol, opioids and their rescue drugs; 3. Patients with the following respiratory risks during screening: acute asthma attack; sleep apnea syndrome; history or family history of malignant hyperthermia; history of tracheal intubation failure; >= III); 4. During the screening period, there is a medical history of gastrointestinal retention, active bleeding, gastroesophageal reflux or obstruction, and the investigator judges that reflux may lead to aspiration; 5. Previous history of neurological and psychiatric diseases: craniocerebral injury, convulsions, epilepsy, intracranial hypertension, cerebral aneurysm, cerebrovascular accident history; or schizophrenia, mania, long-term use of psychotropic drugs, cognitive function History of disorders, etc.; 6. Long-term use of analgesic and sedative drugs in the past, it is not suitable to participate in this study after evaluation by the investigator; 7. Patients with severe heart, liver and kidney diseases during the screening period are not suitable to participate in this study after evaluation by the researchers; 8. Other conditions that the investigator thinks are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygen saturation drop rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen saturation drops;Cough score;Number of body movements;Circulatory system event rate;Onset time;Wake up time;The incidence of injection pain;Proportion of subjects receiving rescue therapy;Satisfaction ratings of patients and bronchoscopists;Satisfaction ratings of patients and bronchoscopists;Bryce Questionnaire; | — |
Countries
China
Contacts
Public ContactMin Yan
Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed