Peri-implantitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Eligible participants are patients diagnosed with periodontitis: 1. With at least one dental implant showing clinical and radiographical signs of peri-implantitis. Periodontitis was defined as follows: probing pocket depth >= 4mm with bleeding on probing and attachment loss >= 3 mm. Peri-implantitis was defined as follows: 2. Probing pocket depth >= 5 mm with concomitant bleeding and/or suppuration on probing and progressive loss of marginal bone >= 2 mm, when compared to the baseline radiograph (after placement of the definitive restoration).
Exclusion criteria
Exclusion criteria: 1. A history of local head and neck radiotherapy; 2. Pregnancy and/or lactation; 3. Uncontrolled diabetes mellitus (HbA1c > 7% or > 53 mmol/mol); 4. Use of antibiotics within 2 months before the baseline assessment; 5. Long-term use of anti-inflammatory drugs; 6. Incapability of performing basal oral hygiene measures; 7. Implants with marginal bone loss >= 3mm; 8. Non-singal-implant supported prosthesis; 9. Being subjected to a previous reconstructive or resective surgical treatment or previous non-surgical treatment of the peri-implantitis within the last 3 months; 10. Severe peridontitis (PD>6mm, AL>= 5mm, bone loss exceeding 1/2 of the length of the tooth).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth; | — |
Countries
China