Distributed Shock Hypotension
Conditions
Interventions
Experiment group:Norepinephrine + Vasopressin Injection
Sponsors
Department of Critical Care Medicine, West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. There is no gender limitation, and the age should be 18-80 years old (including the critical value); 2. Patients with distributed shock within 48 hours who have received fluid resuscitation, norepinephrine treatment dose of 0.2-1.0 µg/kg/min and duration >= 2h; 3. The mean arterial pressure should be 60-70mmHg, and the duration >= 2h; 4. Cardiac index > 2.3L/min/m2; Or the central venous oxygen saturation > 70%, and the central venous pressure > 8 mmHg; 5. Patients or their guardians are willing and able to provide written informed consent and abide by the trial protocol.
Exclusion criteria
Exclusion criteria: 1. Suffering from symptoms such as Raynaud's disease, systemic sclerosis or vasospasm; whooping cough or bronchospasm; acute mesenteric ischemia; aortic dissection or abdominal aortic aneurysm; malignancy; acute coronary syndrome requiring interventional therapy; End-stage liver and kidney failure; Severe cardiac insufficiency, or severe arrhythmia, or heart transplantation, or severe cardiac algal membrane disease, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laboratory tests; | — |
Countries
China
Contacts
Public ContactYan Kang
Outcome results
None listed