The role and mechanism of estradiol-estrogen receptor signaling pathway in precancerous lesions of gastric cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200061159

Enrollment

Unknown

Registered

2022-06-15

Start date

2022-06-01

Completion date

Unknown

Last updated

2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Precancerous lesions of gastric cancer

Interventions

Gastric malignant tumor group,precancerous lesions of gastric cancer (chronic atrophic gastritis, gastric mucosa intestinal metaplasia), chronic superficial gastritis group:none

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing gastroscopy in endoscopy room of our hospital; 2. Patients of different genders and ages (18-70 years old); 3. Patients with chronic superficial gastritis, chronic atrophic gastritis and a gastric malignant tumor under endoscopy.

Exclusion criteria

Exclusion criteria: 1. Complicated with malignant tumors other than gastric malignant tumors; 2. Complicated with serious cardiovascular and cerebrovascular diseases; 3. Complicated with mental illness; 4. Previous long-term medication use.

Design outcomes

Primary

Measure	Time frame
ER-a36;Incidence of precancerous lesions of gastric cancer;ß–catenin;CyclinD1;Caspase-3;	—

Countries

China

Contacts

Public ContactYutao Ma

rmyymyt@163.com+86 15615188703

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026