anesthesia of EBUS-TBNA
Conditions
Interventions
research group:Midazolam-oxycodone-esketamine-propofol induction anesthesia
propofol target-controlled infusion-esketamine constant-rate infusion to maintain anesthesia
control group:Midazolam-oxycodone-propofol induces anesthesia
propofol target-controlled infusion maintains anesthesia
Sponsors
The Second Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-89 years old; 2. ASA classification II-III; 3. The informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. BMI > 28kg/m2; 2. Patients with difficult airway; 3. History of cardiovascular and cerebrovascular adverse events in the past six months, including poorly controlled or untreated hypertension, myocardial infarction, angina pectoris, severe arrhythmia, stroke or transient ischemic attack (TIA) symptom onset; 4. Cognitive dysfunction or mental illness before surgery; 5. Preoperative complicated liver and kidney disease; 6. Preoperative hypoxemia (resting oxygen saturation < 90%); 7. The patient is unable to sign the informed consent and cannot cooperate with the researcher for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The surgeon gives 1%Lidohawen dose (ML/H) by bronchial mirror; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgeon satisfaction;Patient satisfaction;Cough score;Pain score;Oxygen saturation;blood pressure;Heart rate;propofol dose (ml/kg/h);Severavity related adverse reactions; | — |
Countries
China
Contacts
Public ContactLining Huang
Outcome results
None listed