Orbital disease
Conditions
Interventions
Group C:Single-injection of retrobulbar block
Group F:Intravenous flurbiprofen axetil combined with retrobulbar block
Group N:Intravenous nalbuphine combined with retrobulbar block
Sponsors
Zhongshan Ophthalmic Center, Sun Yat-sun University
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 16 to 65 years; 2. with an American Society of Anesthesiologists (ASA) physical status of I or II; 3. who were scheduled to receive orbital implantation under general anesthesia, were included.
Exclusion criteria
Exclusion criteria: 1. Patients were excluded if they had relevant allergies to any medication included in the study protocol; 2. had contraindications to ocular blocks; 3. had current gastrointestinal bleeding or peptic ulcer diseases; 4. had a history of opiate abuse; 5. had chronic pain disorders; 6. cognitive dysfunction that would impede accurate engagement with outcome measurements; 7. had any other factors present likely to influence the study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average pain score within 24 postoperative hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximal pain score within 24 post-operative hours;Cumulated postoperative use of rescue paracetamol from surgery to 24 h;The time to first p.o. paracetamol;Postoperative adverse events;Perioperative data; | — |
Countries
China
Contacts
Public ContactXiaoliang Gan
Zhongshan Ophthalmic Center, Sun Yat-Sen University
Outcome results
None listed