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Clinical study of migraine patients with PFO based on fMRI

Clinical study of migraine patients with PFO based on fMRI

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061113
Enrollment
Unknown
Registered
2022-06-15
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

migraine Patent foramen ovale

Interventions

No patent foramen ovale in normal people:NA
Normal people have patent foramen ovale:NA
Migraine patients without patent foramen ovale:NA
Migraine patients with patent foramen ovale:NA
Migraine patients with patent foramen ovale occlusion:NA

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. It meets the diagnostic criteria of migraine in the third edition of the international classification of headache diseases (ichd-3b), with repeated attacks; (1) 14 years > age age < 70 years; (3) There was no contraindication of MRI and informed consent of patients and their families.

Exclusion criteria

Exclusion criteria: 1. Patients with other types of headache, such as encephalitis, meningitis, cerebrovascular disease, high intracranial pressure, glaucoma, etc; 2. Headache caused by somatization disorder caused by depression and anxiety; 3. Patients with migraine at the time of scanning or within 24 hours after scanning; 4. Those who abuse alcohol and tobacco and have a history of preventive drug use within 1 year; 5. Contraindications to magnetic resonance scanning or claustrophobia; 6. Female subjects were pregnant or in menstrual period; 7. Abnormal cardiac function or history of cerebral infarction.

Design outcomes

Primary

MeasureTime frame
BOLD signal;

Countries

China

Contacts

Public ContactJiajun Yang
yangjiajunfzy@sina.com+86 15821853149

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026