breast cancer
Conditions
Interventions
Treated group:pre-pectoral implant-based Breast Reconstruction combined with TiLoop ? Bra
control group:sub-pectoral implant-based Breast Reconstruction combined with TiLoop ? Bra
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged 18-70 years (including 18 and 70 years); 2. Invasive breast cancer or ductal carcinoma in situ was confirmed by preoperative pathology; 3. (before neoadjuvant chemotherapy) the maximum diameter of breast tumor <= 5cm; 4. patients with clinical cN0 and cN1 (before neoadjuvant chemotherapy); 5. No clinical or imaging evidence of distant metastasis; 6. Subcutaneous gland resection of nipple and areola complex is planned; 7. BMI<40 kg/m2; 8. patients who were allowed to undergo contralateral breast augmentation by endoscopy at the same time; 9. Implant prosthesis< 600 cc; 10. Able and willing to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. patients with inflammatory breast cancer; 2. skin, pectoral muscle, chest wall invasion; 3. Patients with late tumor stage and high risk of recurrence (based on multidisciplinary evaluation); 4. Breast cancer during pregnancy and lactation; 5. scars below the level of the breast papilla and previous radiotherapy history (such as radiotherapy after breast conserving surgery); 6. The patient was complicated with serious disease and poor general condition before surgery and could not tolerate surgery; 7. Immune deficiency; 8. HbA1c > 7.5%; 9. long history of smoking; 10. participating in other clinical studies and may affect participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cosmetic effect;Major complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| minor complications;Economic cost of health;Social psychological health;Breast satisfaction;Sexual satisfaction;Chest health;Capsular contracture rate; | — |
Countries
China
Contacts
Public ContactZhenggui Du
West China Hospital, Sichuan University
Outcome results
None listed