Acute ischemic stroke
Conditions
Interventions
Control group:Aspirin/ Clopidogrel
Sponsors
The Sixth Affiliated Hospital of Jinan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. 18-80 years old; 2. Diagnostic criteria for cerebral infarction in 2018 guidelines for the Diagnosis and treatment of ischemic stroke; 3. NIHSS score is 4-15; 4. CTA/MRA confirmed non-vascular occlusion; 5. <= 8 hours from the onset time or the last seemingly normal time; 6. First stroke, or previous history of stroke without serious sequelae, mRS score <= 2; 7. Obtain informed consent signed by patients or their legally authorized representatives.
Exclusion criteria
Exclusion criteria: 1. Intravenous thrombolysis or mechanical thrombectomy; 2. Uncontrolled persistent hypertension, systolic blood pressure continued >= 180mmHg and/or diastolic blood pressure >= 110mmHg after active blood pressure control; 3.Patients with clear cardiogenic factors leading to cerebral infarction; 4. Coagulation dysfunction or platelet count < 100×10^9/L, bleeding tendency and serious complications such as liver, kidney and heart; 5.A history of major surgery or severe trauma in the last 1 month, and a history of gastrointestinal bleeding in the last 3 months; 6.The pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of early neurological deterioration within 7 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological function prognosis at 90 days;Incidence of symptomatic intracranial hemorrhage(sICH); | — |
Countries
China
Contacts
Public ContactQianru Wen
The Sixth Affiliated Hospital of Jinan University
Outcome results
None listed