Rectal cancer
Conditions
Interventions
Treatment Group:A single incision was made in the right lower abdomen for tumor specimen removal and terminal ileum double lumen fistula
control group:The tumor specimen was taken out through the left lower abdominal incision, and the terminal ileum double-lumen fistula was performed through the right lower abdominal incision
Sponsors
The First Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years; 2. NRS2002 nutrition score < 3; 3. ECOG physical condition score 0-1; 4. Resectable rectal cancer without distant metastasis confirmed by histology or cytology (clinical staging according to AJCC TNM stage 8 consistent with T1-3NXM0); 5. Not receive any preoperative anti-tumor therapy for rectal cancer (including radiotherapy, chemotherapy, targeted therapy, immunotherapy, etc.); 6. Imaging examination indicated that the tumor was located in the lower segment of rectum, and anastomosis with tubular stapler was feasible after resection, and anastomosis was less than 5cm from the anal margin; 7. Patients who can tolerate laparoscopic surgery; 8. Subjects voluntarily joined the study and signed informed consent with good compliance and follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients who received neoadjuvant radiotherapy/chemotherapy before surgery; 2. Patients with intraoperative T4Nx or TxNxM1 rectal cancer; 3. Patients with a history of malignant tumor at the same time or at different times (within 5 years); 4. Patients with a history of abdominal and pelvic surgery; 5. Patients with tumors or metastases in perirectal organs or pelvic floor need to be excised with perirectal organs; 6. Severe intestinal edema at the proximal end of anastomosis caused by intestinal obstruction and other factors; 7. Patients with extensive abdominal inflammation, such as intestinal perforation or intestinal bleeding, need emergency surgery; 8. ASA grade IV-V; 9. Serious cardiovascular diseases, uncontrollable infections or uncontrollable co-morbidities; 10. Patients or family members who do not accept preventive fistula; 11. Unable to complete the test program or follow-up plan due to family, social or geographical conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incision healing grade;ostomy complications;unplanned secondary operation rate;Operation time;suture time of fistula;VAS score of postoperative pain; | — |
Countries
China
Contacts
Public ContactLi Yunlong
The First Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed