Decreased ovarian reserve function
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meeting the Western diagnostic criteria for DOR; 2. Consistent with the TCM diagnosis of liver and kidney yin deficiency; 3. No pregnancy requirement for the last 3 menstrual cycles; 4. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Primary or secondary amenorrhea due to congenital abnormalities of the reproductive organs or acquired organic lesions and injuries; 2. Severe primary diseases of the cardiovascular, hepatic, renal and hematopoietic systems; suspected psychiatric patients; patients with diabetes; 3. Bilateral or unilateral oophorectomy; 4. Known or suspected breast cancer; known or suspected precancerous or malignant tumors affected by sex hormones; 5. Acute arterial thromboembolism, active venous thrombosis, thromboembolic disease or history of thromboembolic disease, or risk factors for venous or arterial thrombosis risk factors; 6. Hormone use within the last 2 months; 7. Hypersensitivity to the components of this drug; 8. Severe hypertriglyceridemia; 9. Subjects whose compliance is judged by the investigator to be poor, whose efficacy cannot be judged, or whose data are incomplete, which affects the determination of efficacy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-Mullerian hormone;Folliculopoietin;Luteinizing hormone;Estradiol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese Medicine Evidence Scoring Scale;Modified Menopause Kupperman Rating;Hamilton Anxiety Inventory; | — |
Countries
China
Contacts
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine