Burn
Conditions
Interventions
Es group:Small doses of esketamine are given intravenously
Control group:Intravenous injection of an equal volume of 0.9% normal saline
Sponsors
The Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults under the age of 60 years old; 2. ASA Grade II to III; 3. Burn area 30%-60%, burn depth of deep II degree and III degree; 4. The burn site involves the trunk and limbs of the body, and there is no serious liver and kidney function damage; 5. Primary school and above education level, able to do questionnaire surveys.
Exclusion criteria
Exclusion criteria: 1. Patients with serious primary diseases such as cardiovascular, cerebrovascular, hepatic and renal and hematopoietic systems; 2. Patients with severe burn fluid exudation period, wound repair period and rehabilitation period, patients with serious complications; 3. Patients with mental disorders and difficulty communicating; 4. History of drug allergies, severe liver and kidney dysfunction, blood system dysfunction and severe system symptoms such as sepsis, high fever and chills; 5. Tracheostomy has been performed with burns from special parts such as the respiratory tract; 6. Patients or patients' families are reluctant to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sas; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of hemodynamic indicators at different time points;Comparison of intraoperative cardiovascular adverse events;Postoperative pain level; | — |
Countries
China
Contacts
Public ContactZhang Zhongjun
The Affiliated
Outcome results
None listed