non-small cell lung cancer
Conditions
Interventions
PTC-Multimodal interventional treatment :Multimodal interventional treatment
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-85 years, with biopsy proven NSCLC; 2. American Joint Committee on Cancer (AJCC)Version 8, TNM StageIII NSCLC; 3. Patients who cannot be resected surgically, fail radiotherapy and chemotherapy, or are intolerant; 4. Estimated survival > 3 months; 5. ECOG PS 0-3; 6. Radio-chemotherapy failure was defined as dynamic re-examination of enhanced CT every 6-8 weeks after receiving first-line chemotherapy according to RECIST 1.1. as disease progression; 7. Patients who could not receive radiotherapy and chemotherapy included patients with ECOG PS score of 3 and refused to receive first-line chemotherapy due to old age or personal wishes; 8. The functional level of major organs must meet the following requirements: (1) CBC neutrophils >= 1.5x10^9/L, PLT >= 90x10^9/L, HGB >= 90g/L; (2) Blood biochemistry TB <= upper limit of normal value(ULN), ALT & AST <= 1.5xULN, nitrogen & creatinine <= 1.5xULN.
Exclusion criteria
Exclusion criteria: 1. < 18 years old; 2. Previously received TKI or immunotherapy; 3. Estimated survival < 3 months; 4. At the same time, he received anti-tumor therapy in other clinical trials, including immunotherapy, TKI and so on; 5. A history of immune deficiency or other acquired congenital immune deficiency diseases or a history of organ transplantation; 6. Other circumstances in which the investigator determines that it is not appropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PSF; | — |
Secondary
| Measure | Time frame |
|---|---|
| ORR;DCR;OS;QoL; | — |
Countries
China
Contacts
Public ContactLi Xiao-Guang
Beijing Hospital, National Center of Gerontology
Outcome results
None listed