Respiratory system complications in patients undergoing tonsillectomy and/or adenoidectomy
Conditions
Interventions
A:Different doses of sufentanil in patients 3-6 years of age
B:Different doses of sufentanil in patients 6-9 years of age
C:Different doses of sufentanil in patients 9-15 years of age
D:Different doses of sufentanil in patients over 15 years of age
Sponsors
Yichang Central People's Hospital of Hubei Province
Eligibility
Sex/Gender
All
Age
3 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 3-65 years; 2. ASA class I or II; 3. Estimated anesthesia operation time <= 120min; 4. BMI 14-23.9kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of opioid allergy; 2. Analgesics, sedatives, emetics and anti pruritus drugs were used 24 hours before operation; 3. Patients with body temperature higher than 38 ? within 24 hours before operation or with symptoms of acute upper respiratory tract infection; 4.Patients with a history of bronchial asthma; 5. Patients diagnosed with moderate to severe sleep apnea syndrome before operation; 6. Patients with difficult airway or previous abnormal anesthesia recovery history were evaluated before operation; 7. Renal function injury (BUN and or Cr > upper limit of normal value); 8. Liver function injury (ALT and or ast > 1.5 times the upper limit of normal value); 9. Patients with severe head trauma and intracranial hypertension within 6 months; 10. Patients with mental and neurological diseases, or unable to correctly express their wishes; 11. Patients with long-term sedative and analgesic drugs or monoamine oxidase inhibitors; 12. The estimated blood loss is more than 100ml; 13. Those who have participated in clinical trials of other drugs in recent one month; 14. Patients who can't score ASA or flacc for various reasons; 15. With other conditions, the researchers believe that it is not suitable for the selected patients; 16. Abnormal breath holding test; 17. Haven't quit smoking in the last half month; 18. Patients with hypertension or accompanied by arrhythmia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The grade for SIC;The grade for EIC;Score for Throat pain;ED50 for SIC;ED50 for EIC;ED50 for Throat pain;Incidence of analgesic use;Incidence of PONV; Score for Throat pain in 24h;Hemodynamic parameters within five minutes after induction of intubation;Hemodynamic indexes within five minutes after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time for extubation; | — |
Countries
China
Contacts
Public ContactGong Yuan
Yichang Central People's Hospital of Hubei Province, 183 Yiling Avenue, Yichang, Hubei
Outcome results
None listed