Subthreshold Depression
Conditions
Interventions
subthreshold depression intervention group:health education/Internet-based Cognitive Behavioral Therapy
subthreshold depression control group:none
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Depression group (1) Aged 18-65 years; (2) Diagnosed as first-episode or recurrent depressive episode according to ICD-10; (3) Voluntarily participate and sign informed consent. 2. Subthreshold depression group (1) Aged 18-65 years; (2) Subthreshold depression determined according to MINI5.0, with any two to three symptoms, and does not meet the diagnostic criteria for depression; (3) Voluntarily signed informed consent. 3. Healthy control group (1) Aged 18-65 years; (2) Have one or no symptoms; (3) HAMD-17 < 8 points, PHQ-9 < 5 points, GAD-7 < 5 points; (4) No history of mental illness; (5) Voluntarily signed informed consent Book.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women, patients who are unwilling to take contraceptive measures during the study period; 2. Patients with severe or unstable diseases who are judged unsuitable for participation in this study by the researchers; 3. Patients with history of serious neurological diseases (including epilepsy, seizures, brain injury, multiple sclerosis, degenerative diseases such as acute lateral sclerosis, Parkinson's disease and ataxia).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SDS deduction rate;Kappa vale;Sensitivity;specificity;Youden Index;Receiver operator characteristic curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knowledge awareness rate;positive predictive value; | — |
Countries
China
Contacts
Public ContactDong Wentian
Peking University Sixth Hospital
Outcome results
None listed