the mechanism of hyperbaric oxygen in the treatment of severe heat stroke with multiple organ dysfunction

the mechanism of early hyperbaric oxygen in the treatment of severe heatstroke induced by military training with multiple organ dysfunction

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200060981

Enrollment

Unknown

Registered

2022-06-14

Start date

2022-06-01

Completion date

Unknown

Last updated

2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heat stroke

Interventions

Hyperbaric oxygen treatment:Hyperbaric oxygen treatment

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? Clinical diagnosis of severe heatstroke (neurological impairment complicated with MODS); ? The diagnosis criteria of severe heat stroke were still met in acute stage (within 1 week) or more than 1 week of onset. (3) Education level in primary school or above; ? Receiving HBO treatment; ? Right handedness (according to the Chinese handedness assessment standard).

Exclusion criteria

Exclusion criteria: ? History of craniocerebral trauma, encephalitis, cerebrovascular accident, chronic cirrhosis, renal fibrosis, myocardial infarction, and other history of intracranial/heart/liver/kidney space occupation; ? Have a long history of alcoholism, mental illness or drug abuse; ? Age =18 years or =60 years; ? The patient is unable or unwilling to undergo examination or treatment.

Design outcomes

Primary

Measure	Time frame
MR imaging;The biochemical indicators;	—

Secondary

Measure	Time frame
Neuroelectrophysiological results;Apoptosis index;Oxidative damage index;Inflammatory biomarkers;	—

Countries

China

Contacts

Public ContactXiao-xiao Ni

nxx373@hotmail.com18826469064

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026