Titrate PEEP combined with recruitment manoeuvres according to pneumoperitoneal pressure values in laparoscopic surgery in children: a randomized, double-blind study

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200060980

Enrollment

Unknown

Registered

2022-06-14

Start date

2022-06-01

Completion date

Unknown

Last updated

2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atelectasis

Interventions

Conventional ventilation group:PEEP=0 cm H20

pneumoperitoneum pressure group:PEEP adjusted according to pneumoperitoneum pressure

RM+Conventional ventilation group:RM+PEEP=0 cm H20

RM+pneumoperitoneum pressure group:RM+PEEP adjusted according to pneumoperitoneum pressure

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: (1) Children younger than 18 years of age; (2) American Society of Anesthesiologists (ASA) physical status I-III (3) Undergoing general anesthesia laparoscopic surgery

Exclusion criteria

Exclusion criteria: (1) history of anesthetic allergy; (2) significant cardiovascular, respiratory, and central nervous system; (3) recent respiratory tract infection; (4) abnormal preoperative chest X-ray or CT examination, including pulmonary atelectasis, pneumothorax, pleural effusion, or pneumonia.

Design outcomes

Primary

Measure	Time frame
Pulmonary consolidation score;b line score;	—

Secondary

Measure	Time frame
Change in cycle index;Changes of respiratory indexes;	—

Contacts

Public ContactLi-Ming CHENG

Medcheng@126.com13888764840

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026