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Comparison of short and long term outcomes between open and laparoscopic gastrectomy for locally advanced gastric cancer after neoadjuvant chemotherapy: A propensity score matching comparative study

Comparison of short and long term outcomes between open and laparoscopic gastrectomy for locally advanced gastric cancer after neoadjuvant chemotherapy: A propensity score matching comparative study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060966
Enrollment
Unknown
Registered
2022-06-14
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

laparoscopic gastrectomy group:Nil
open gastrectomy group:Nil

Sponsors

Department of Gastrointestinal Surgery, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Eligible participants were between 18 and 80 years of age with histologically confirmed gastric adenocarcinoma according to the Eighth Edition of the American Joint Committee on Cancer (AJCC) staging system, with a clinical stage of cT2-4aN+M0 at preoperative evaluation. The clinical TNM stage was determined using computed tomography (CT) scan and endoscopic ultrasonography. All patients received 2-4 cycles of platinum-based chemotherapy regimens preoperatively. Surgery was performed 3 to 6 weeks after the completion of preoperative chemotherapy.

Exclusion criteria

Exclusion criteria: neoadjuvant radiotherapy, lymph node metastasis outside the extent of the D2 resection, cT4b, intraoperative frozen pathology confirmed distant metastasis, loss to follow-up.

Design outcomes

Primary

MeasureTime frame
Overall Survival;Relapse Free Survival;Complication rate within 30 days after surgery;

Countries

China

Contacts

Public ContactYanbing Zhou

Department of Gastrointestinal Surgery, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China

zhouyanbing@qduhospital.cn13708971773

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026