Individualized study in children with sepsis based on population pharmacokinetic models of antibiotics

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200060964

Enrollment

Unknown

Registered

2022-06-14

Start date

2022-07-01

Completion date

Unknown

Last updated

2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious Diseases in Children

Interventions

Case series :nil

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1.Aged from 1 month to 18 years. 2.Diagnosed as children with sepsis. the specific diagnostic criteria refer to the SOFA score in the 2018 "Guidelines for emergency treatment of sepsis and septic shock in China". 3.The hospital stays exceeded 5 half-lives of antibiotics.

Exclusion criteria

Exclusion criteria: 1.The inpatients who received blood transfusion. 2.No detection method. 3.Refusal to sign informed consent. 4.Treated with blood purification therapy. 5.The application time of some antibacterial drugs did not reach 5 half-lives.

Design outcomes

Primary

Measure	Time frame
blood concentration;	—

Countries

China

Contacts

Public ContactYue Wu

Shenzhen Children's Hospital

wuyue161@163.com18938690526

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026