Knee osteoarthritis
Conditions
Interventions
Group A:PAI 1g(10ml)TXA+IAI 20ml NS
Group B:PAI 10ml NS+IAI 2g (20ml) TXA
Sponsors
Xi'an Honghui Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 50 to 80 years with primary unilateral or bilateral knee osteoarthritis; 2.Primary unilateral total knee arthroplasty was performed;3.Good physical condition, can tolerate surgery; 4.Preoperative coagulation function of hemoglobin erythrocyte sedimentation rate and C-reactive protein were normal; 5.There was no abnormality in deep vein ultrasonography of both lower limbs pre-operative.
Exclusion criteria
Exclusion criteria: 1) The patient had a history of tranexamic acid allergy; 2) history of thrombosis and oral anticoagulants within two weeks; 3) have ongoing infections in other parts of the body; 4) Hemorrhagic diseases; 5) Atrial fibrillation, angina pectoris, stroke and other internal diseases; 6) Rheumatoid arthritis; 7)TKA revision patients; 8) The patient had a mental illness or refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood loss volume;transfusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| ROM;VAS; | — |
Countries
China
Contacts
Public ContactJianpeng Wang
Outcome results
None listed