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The protective effect and neuroplasticity of different stimulation targets of rTMS on motor dysfunction after ischemic stroke

The protective effect and neuroplasticity of different stimulation targets of rTMS on motor dysfunction after ischemic stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060955
Enrollment
Unknown
Registered
2022-06-14
Start date
2022-06-01
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

None listed

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?Patients with ischemic stroke who meet the diagnostic criteria in "Key Points for the Diagnosis of Various Major Cerebrovascular Diseases in China 2019" formulated by the Neurology Branch of the Chinese Medical Association, and are diagnosed with ischemic stroke by cranial spiral CT or cranial magnetic resonance imaging;?The responsible lesion was first onset, and after clinical evaluation, there were various degrees of motor dysfunction;?The course of the disease is between 1 month and 3 months;?Right-handed;?Gender is not limited, age between 40-80 years old; ?Vital signs are stable, consciousness is clear, MMSE>21 points; ?Sign the informed consent.

Exclusion criteria

Exclusion criteria: ?Unstable disease, progressive stroke or secondary stroke;?The affected side has previous peripheral nerve injury or peripheral neuropathy;?Have a history of epilepsy or family history;?Severe anxiety-depressive symptoms that require drug control;?Severe heart, lung, liver, kidney and other organ diseases;?Have a pacemaker, cochlear implant, or cranioplasty in the body;?Patients with claustrophobia.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment ,FMA;Berg balance scale,BBS;modified Ashworth scale,MAS;

Secondary

MeasureTime frame
NIH Stroke Scale,NIHSS;Modified Barthel Index,MBI;Hamilton Anxiety Scale,HAMA;Hamilton Depression Scale,HAMD;Minimum Mental State Examination,MMSE;functional magnetic resonance imaging,FMRI;functional near - infrared spectroscopy , fNIRS;

Countries

China

Contacts

Public ContactChunxiao Wan
wcx2226@163.com18522956917

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026