acute respiratory distress syndrome
Conditions
Interventions
Treatment group:Plasmapheresis
Control group:None
Sponsors
The First People's Hospital of Chenzhou
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) The diagnosis met the "2012 Diagnostic criteria for ARDS -- Berlin New Definition; (2) Age > 18; (3) Receiving ICU treatment; (4) Did not participate in other clinical studies; (5) One or more of the following symptoms: I Oxygenation index < 300 II after adequate fluid resuscitation, vasoactive agents are required to maintain MVP=65mmHg or lactic acid =2.0mmmol/l III. Multiple organ dysfunction.
Exclusion criteria
Exclusion criteria: (1) complicated with end-stage tumor, or complicated with end-stage of other chronic diseases, such as immune deficiency or significant immunosuppression; (2) Pulmonary embolism, interstitial pneumonia or other serious pulmonary diseases; (3) primary severe organ dysfunction; (4) Contraindications of plasma exchange (5) pregnant women; (6) Refusal to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum inflammatory factor;Mechanical ventilation time;Length of ICU stay;SOFA score;Oxygenation index; | — |
Countries
China
Contacts
Public ContactLi Tao
Outcome results
None listed