Lung cancer and pulmonary nodules
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA level I to III; 2. Age>=18 years old; 3. Body mass index 18-35; 4. All patients underwent lung lobectomy under general anesthesia with one lung ventilation under thoracoscope; 5. All operations were performed under general anesthesia or combined with superior laryngeal nerve block; 6. All anesthesia and surgical management are conducted by the same team; 7. The patient signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to general anesthesia; 2. Serious heart, liver, or kidney disease; 3. History of mental disorders or excessive use of opioid analgesics; 4. Taking drugs that affect blood pressure and heart rate for a long time; 5. Electrolyte disorder; 6. Patients predicted to have difficult airways; 7. History of surgery/anesthesia within 6 months; 8. Contradictions or complications of superior laryngeal nerve block, including coagulation dysfunction, local infection, and local anesthetic toxicity; 9. Conversion to open chest surgery; 10. Patients with long-term poor blood glucose control/diabetes before surgery; 11. Patients with metabolic disorders associated with increased/decreased cortisol; 12. Patients with severe cognitive impairment or language problems; 13. History of POST,hoarseness, and cough before operation; 14. History of acute upper respiratory tract infection within 1 week before surgery; combined with asthma and COPD; 15. Patients who have not signed an informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sore throat 6 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sore throat 2 hour after surgery;Sore throat 24 hour after surgery;Severity of POST after surgery;hoarseness after surgery;Severity of hoarseness after surgery; | — |
Countries
China
Contacts
Department of Anesthesiology, the Second Hospital, Cheeloo College of Medicine, Shandong University