Study on epigenetic mechanism of clock gene in bipolar disorder and the effect of light therapy on depressive episodes of bipolar disorder

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200060872

Enrollment

Unknown

Registered

2022-06-13

Start date

2022-06-01

Completion date

Unknown

Last updated

2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar disorder

Interventions

Light treatment group and experimental control group:Bright light therapy

Eligibility

Sex/Gender

All

Age

14 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.18-50 years old, Han nationality; 2.No family history of psychosis, Hamilton Depression Scale (24 items) > 18 points, signed informed consent.

Exclusion criteria

Exclusion criteria: 1.co-existing with other DSM-IV axis I, AXIS II mental disorders or substance abuse (except smokers) or with epilepsy or cognitive disorders; 2. Associated with serious physical diseases or organic lesions in the brain, such as serious heart, liver, kidney and other organ dysfunction, malignant tumors, etc; 3.Women who are pregnant or breastfeeding; 4. Malnourished or obese (BMI =30); 5.Patients who had used psychotropic drugs, such as antidepressants, antimanic drugs or other drugs used to treat psychosis, in the 2 weeks prior to the study; 6.Have serious suicidal idea or suicidal behavior; 7.Failure to sign informed consent.

Design outcomes

Primary

Measure	Time frame
DNA Methylation;	—

Countries

China

Contacts

Public ContactWang Yumei

wangyumei19771021@hotmail.com+86 18633889983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026