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Biomarkers and etiological mechanisms of the development of aortic dissection

Biomarkers and etiological mechanisms of the development of aortic dissection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060863
Enrollment
Unknown
Registered
2022-06-12
Start date
2022-06-01
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Dissection

Interventions

Sponsors

The Second Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: This study included patients with aortic dissection and aortic valve replacement who were treated in a cardiovascular center, as well as those who underwent physical examination in the hospital during the same period;

Exclusion criteria

Exclusion criteria: Patients with connective tissue diseases such as Marfan syndrome, traumatic aortic dissection, tumors, etc.;

Design outcomes

Primary

MeasureTime frame
Basic Information Questionnaire;Clinical Information Sheet;metabolomics;Single-cell sequencing;Spatial Transcriptomics;Whole Genome Sequencing;Proteomics;Transcriptomics;Follow-up Information Sheet;Serum heavy metal content;

Secondary

MeasureTime frame
HE staining of aortic wall;Verhoff staining of elastin fibers;Masson's trichrome staining of collagen fibers;Aortic wall immunofluorescence staining;Aortic wall ultrastructure;

Countries

China

Contacts

Public ContactQingguo Li

The Second Affiliated Hospital of Nanjing Medical University

liqg@njmu.edu.cn+86 13913899923

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026