obesity
Conditions
Interventions
test group:Oral synbiotics
Control group:Oral placebo
Sponsors
Department of gastrointestinal surgery, the First Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65; 2. 28<=BMI<=35Kg/m2 3. Be willing and able to follow the plan during the study and cooperate to complete various inspections during the test. Provide written informed consent before entering the study screening, and the patient has learned that he can withdraw from the study at any time without any loss;
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women who are in the reproductive period and do not take contraceptive measures; 2. Oral antibiotics nearly 1 month before enrollment; 3. Probiotics and prebiotic products were used 3 weeks before intervention; 4. People who have a fitness and fat reduction plan during the intervention period or plan to have gastric surgery; 5. Patients with severe gastrointestinal diseases; 6. Known allergy to synbiotics or similar products; 7. Patients without self-knowledge ability and persons with mental disorders; 8. Have a history of organ transplantation or malignant tumor diseases; 9. Use other test drugs at the same time or in other clinical trials; 10. Have a history of alcohol, tobacco and other drug abuse; 11. Those who are expected to be unable to complete the magnetic resonance examination; 12. Patients taking various kinds of mental disease control drugs; 13. Complicated with serious medical diseases or conditions: such as clinically serious (i.e. active) heart disease, serious and uncontrolled medical diseases and infections, serious uncontrollable digestive system disorders, serious electrolyte disorders, active disseminated intravascular coagulation, major organ failure, such as decompensated heart, lung, liver, kidney failure, peripheral neuropathy, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body mass index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal flora; | — |
Countries
China
Contacts
Public ContactJigang
Outcome results
None listed