Parkinson's disease
Conditions
Interventions
intervention group:Progressive inspiratory resistance training
control group:Mendelson
Sponsors
Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria were in accordance with the 2016 Chinese Parkinson's Disease Guidelines issued by the Chinese Society of Neurology; 2. A certain degree of dysphagia as assessed by the scale (e.g., cough during meals and prolonged eating time); 3. Aged 50-80 years; 4. Hoehn-yahr grading was stage II-IV; 5. MMSE 24 or more; 6. Continued stable medication regimen (dose and drug type) during the study; 7. Patients gave informed consent and voluntarily participated in the study.
Exclusion criteria
Exclusion criteria: 1. Other neurodegenerative diseases or serious cerebrovascular diseases; 2. Severe digestive, respiratory and cardiovascular diseases; 3. Associated with head and neck tumor or nasal septum foreign body; 4. Smoking history in recent 3 years; 5. Compliance difficulties caused by severe mental and psychological diseases; 6. It is difficult to maintain proper oral seal or avoid air leakage in lung function test; 7. Taking other investigational drugs or participating in other clinical trials within 3 months prior to study inclusion; 8. For any reason not suitable for the study or not suitable for inclusion in the study as considered by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fiberoptic Endoscopic Evaluation of Swallowing;Water swallow scale;swallowing quality of life questionaire;unified Parkinson disease ration scale;Pulmonary function test; | — |
Secondary
| Measure | Time frame |
|---|---|
| modified water swallow test;Parkinson disease quality;activities of daily living;Mini-mental state Examination;Hamilton Depression Scale;Borg index;10-meter walk test;Tinetti balance and gait analysis; | — |
Countries
China
Contacts
Public ContactLi Qin
Second Affiliated Hospital of Army Medical University
Outcome results
None listed