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The effect of adjunctive intravitreal conbercept at the end of 25G vitrectomy in severe proliferative diabetic retinopathy

The effect of adjunctive intravitreal conbercept at the end of 25G vitrectomy in severe proliferative diabetic retinopathy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060735
Enrollment
Unknown
Registered
2022-06-09
Start date
2022-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic retinopathy

Interventions

Group A:No intravitreal injection of conbercept during pars plana vitrectomy
Group B:intravitreal injection of conbercept during pars plana vitrectomy

Sponsors

Tongji Hospital of Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years, and the gender is not limited; 2. Activity PDR, with vitreous bleeding and/or retina fiber vascular membrane; 3. All patients are detailed in eye examinations that meet serious PDR; 4. Signing the consent of informed consent and agreed to use the information for clinical research.

Exclusion criteria

Exclusion criteria: 1. Combined with eye diseases that affect vision, such as RVO, AMD, etc.; 2. History of PPV surgery; 3. Intravitreal injection or retina photocoagulation within 6 months before surgery; 4. NVG; 5. severe eye infection; 6. Use anticoagulation or antiplatelet drugs; 7. Poor diabetes before or after surgery; 8. There are serious systemic diseases; 9. Pregnant women; 10. Allergy to Conbercept; 11. The postoperative follow-up time is less than 6 months.

Design outcomes

Primary

MeasureTime frame
recurrence of early and late vitreous hemorrhage;

Secondary

MeasureTime frame
best corrected visual acuity;intraocular pressure;macular fovea thickness;

Countries

China

Contacts

Public ContactHoushuo Li

Tongji Hospital of Tongji University

lihsh2009@hotmail.com+86 137742409621

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026