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Effects of rocuronium-induced neuromuscular blockade on intraoperative transcranial electrical facial nerve motor evoked potentials in patients undergoing resection of acoustic neuroma

Effects of rocuronium-induced neuromuscular blockade on intraoperative transcranial electrical facial nerve motor evoked potentials in patients undergoing resection of acoustic neuroma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060731
Enrollment
Unknown
Registered
2022-06-09
Start date
2022-05-31
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acoustic neuroma

Interventions

no NMB group:None
partial NMB group:None

Sponsors

Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years; 2. American Society of Anesthesiologists (ASA) physical statuses I-II.

Exclusion criteria

Exclusion criteria: 1. Patients known to be allergic to the drugs (e.g., rocuronium, propofol, remifentanil, and so on) contained in the test; 2. Patients with contraindications in performing transcranial electrical stimulation (including patients with a history of epilepsy, and patients implanted brain stimulation electrodes, stimulators , and pacemakers); 3. Patients with a history of forearm surgery and suffering from dysfunction of peripheral nerves and muscles; 4. House–Brackmann grades III to VI; 5. Obese patients (BMI >= 30 kg/m2).

Design outcomes

Primary

MeasureTime frame
the minimum stimulating voltage required for eliciting Tce-FNMEP of the orbicularis muscle (Vmouth);

Secondary

MeasureTime frame
The minimum stimulating voltage required for eliciting Tce-FNMEP of the five (or as many as possible) facial muscle groups (Vmulti);the "elicitation rate", and the latency and amplitude of Tce-FNMEP of the five different facial muscle groups at a voltage of Vmouth;the "elicitation rate", and the latency and amplitude of Tce-FNMEP of the five different facial muscle groups at a voltage of Vmulti;

Countries

China

Contacts

Public ContactQiong Yu

Huashan Hospital, Fudan University

yu.qiong816@qq.com+86 14772755168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026