Senile Depression
Conditions
Interventions
General Aerobic exercise Group:General Aerobic exercise
Blank Control Group:None
Sponsors
West China Second University Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 60 years; 2. Have lived stably in the same community for at least one year; 3. Physical condition allows regular exercise; 4. Normal hearing; 5. Have the ability to cooperate with questionnaire filling; 6.A PHQ-9 score of 5 or higher.
Exclusion criteria
Exclusion criteria: 1. Have contraindications to exercise (e.g., severe hypertension, stroke history within the last 6 months, etc.); 2. Those who regularly practice Tai Chi or other aerobic exercises in the past 1 year; 3. Patients with major depression (PHQ-9 score 20 or higher).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain-derived neurotrophic factor methylation level;Patient Health Questionnaire-9 score;nicotinamide adenine dinucleotide expression level;Sirtuin1 expression level;brain-derived neurotrophic factor expression level; | — |
Countries
China
Contacts
Public ContactLiao Shujuan
West China Second University Hospital
Outcome results
None listed