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The therapeutic effect of paxlovid combined with conventional therapy in patients aged 60 and over with COVID-19

A non randomized controlled trial to evaluate the efficacy of paxlovid combined with conventional therapy in patients aged 60 and over with COVID-19 mainly caused by Omicron infection

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060700
Enrollment
Unknown
Registered
2022-06-08
Start date
2022-05-27
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID 19

Interventions

Intervention group:Paxlovid combined with routine treatment
Control group:Routine treatment

Sponsors

The Ninth People Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
61 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1.Patients with confirmed COVID-19 and not receiving systematic treatment 2.Patients with paxlovid treatment indications in accordance with the diagnosis and treatment scheme for novel coronavirus (trial version 9) 3.Age >= 60 4.All patients who did not have drug contraindications and agreed to paxlovid treatment were included in the trial group 5.All patients who used drugs prohibited to be combined with paxlovid, such as amiodarone, carbamazepine, diazepam and phenobarbital, were included in the control group 6.Voluntary or authorized agent to sign informed consent

Exclusion criteria

Exclusion criteria: 1.Recently, the patients with new coronal infection became negative and then became positive again; 2.Patients with second or more infections.

Design outcomes

Primary

MeasureTime frame
Nucleic acid shedding time;

Secondary

MeasureTime frame
Severe rate;Symptom disappearance time;Adverse events;

Countries

China

Contacts

Public ContactLi Yi

The Ninth People Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

snailliyi@163.com+86 13774220418

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026