cervical cancer
Conditions
Interventions
Experimental group:D-TACE+Standard chemoradiotherapy
Sponsors
Lishui Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 18-75, with no gender limitation; 2) Cervical cancer was diagnosed clinically by histopathological and cytological examination; 3) Patients who have no clinical indications for surgery and cannot be surgically resected or refused surgery; 4) Physical fitness ECOG-PS <=1; 5) The expected survival time is more than 3 months; 6) There is at least one evaluable lesion in the lesion, and the diameter of the lesion can be measured; 7) Subjects voluntarily joined the study and signed informed consent with good compliance and follow-up.
Exclusion criteria
Exclusion criteria: 1) Distant metastasis of tumor; 2) those who have had or are currently having other malignant tumors (except cured basal or squamous cell skin cancer or carcinoma in situ of the cervix); 3) Patients in the experimental group with tumor supplying artery overselection failure; 4) a history of major diseases involving the heart, kidney, bone marrow or lung or central nervous system; 5) Recent infections requiring antibiotic treatment; 6) Abnormal liver and kidney functions (transaminase was 5 times the normal value, bilirubin increased 50 mmol/L, albumin < 28 g/L, creatinine clearance < 50 mL/min); 7) Abnormal coagulation function, marked reduction of peripheral white blood cells and platelets (WBC < 3*10^9/L, platelets < 50*10^9/L), which cannot be corrected; 8) Patients with contraindications for vascular intervention, contrast agents or study drugs; 9) Pregnant or lactating women, or fertile women who are unwilling or unable to take effective contraceptive measures; 10) Participating in other clinical trials or judging by other researchers that may affect the conduct of the clinical study and the determination of the study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival;Objective Response Rate;Disease Control Rate;Duration of Response; | — |
Countries
China
Contacts
Public ContactZhongwei Zhao
Lishui Central Hospital
Outcome results
None listed