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Analgetic efficacy and safety of Thoracoscopic-guided Multiple Paravertebral Block for Video-assisted Thoracoscopic Lobectomy Surgery and early postoperative analgesia: A Randomized Blinded Controlled Study

Analgetic efficacy and safety of Thoracoscopic-guided Multiple Paravertebral Block for Video-assisted Thoracoscopic Lobectomy Surgery and early postoperative analgesia: A Randomized Blinded Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060675
Enrollment
Unknown
Registered
2022-06-07
Start date
2022-04-25
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

video-assisted thoracoscopic lobectomy

Interventions

control group:general anesthesia and thoracoscopic-guided thoracic paravertebral block with placebo
PVB group:thoracoscopic-guided thoracic paravertebral block

Sponsors

Putian First Hospital, Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The study enrolled 60 ASA I-III patients (18-65 years old, either gender, weighing 50-85 kg) who were scheduled to undergo elective thoracoscopic lobectomy. Patients undergoing elective general anesthesia and video-assisted thoracoscopic unilateral lobectomy had no history of cardiopulmonary disease, no sinus bradycardia, no functional lesions of the sinoatrial node, no serious arrhythmia, and no thoracic deformity. Surgery time was more than 2 hours.

Exclusion criteria

Exclusion criteria: Exclusion criteria: minimental state examination scores below 23 points; the history of dementia, psychosis, or other central nervous system disease or drug dependence and poor compliance; and those who did not complete video-assisted thoracoscopic lobectomy under general anesthesia or have to convert to thoracotomy.

Design outcomes

Primary

MeasureTime frame
intraoperative opioid consumption;total sufentanil dosages within the first 48h postoperatively;postoperative NRS scores;

Secondary

MeasureTime frame
Ramsay sedation scores;first use of patient-controlled analgesia (PCIA) intravenously;the pressing times of analgesic pumps;QoR-40 scores;

Countries

China

Contacts

Public ContactYaohua Yu

Putian First Hospital, Fujian Medical University

yuyhanesthesia@163.com+86 135 0119 0076

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026