Biliary tract cancers
Conditions
Interventions
Chemo holiday cohort:Received chemo holiday
Conventional chemotherapy cohort:Received conventional chemotherapy
Sponsors
Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years old; 2. Postoperative pathological diagnosis of biliary tract cancers with negative margins and positive lymph nodes; 3. Received adjuvant chemotherapy; 4. Without medical history of other malignancy; 5. With available postoperative follow-up (>=3 months).
Exclusion criteria
Exclusion criteria: 1. Insufficient data quality; 2. Patients who previously received systemic therapy with PD1 antibody, PDL1 antibody, CTLA4 antibody, TKI inhibitor, or chemotherapy; 3. Vulnerable groups, including people with mental illness, cognitive impairment, critically ill patients, minors, pregnant women, etc.; 4. With positive resection margin; 5. Undergo palliative surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemotherapy completion;Recurrence-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Adverse events;Quality of life; | — |
Countries
China
Contacts
Public ContactMingyu Chen
Outcome results
None listed