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Effect of laparoscopic sleeve gastrectomy on periodontal health status and oral microbiota of obese patients with type 2 diabetes mellitus

Effect of laparoscopic sleeve gastrectomy on periodontal health status of obese patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060644
Enrollment
Unknown
Registered
2022-06-06
Start date
2022-07-01
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

Sugery Group:laparoscopic sleeve gastrectomy

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years old; 2. Body mass index (BMI) >= 27.5kg/m2; 3. Patients clinically diagnosed as T2DM; 4. Patients clinically diagnosed with periodontitis; 5. Have not received periodontitis treatment in the past six months; 6. At least 16 remaining teeth; 7.Consent to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Smokers; 2. Pregnant or lactating women; 3. Have a history of radiation therapy for the head and neck; 4. Long-term use of nonsteroidal anti-inflammatory drugs, corticosteroids, tetracyclines, bisphosphates or other drugs that affect bone regeneration; 5. Teeth are obviously crowded, ectopic, twisted; 6. Have acute infection of the tooth; 7. Abuse of drugs or alcohol or have poorly controlled mental illness; 8. Poor general condition, difficult to tolerate anesthesia or surgery.

Design outcomes

Primary

MeasureTime frame
plaque index;probing depth;bleeding index;clinical attachment loss;oral bacteria;

Secondary

MeasureTime frame
body mass index;Total weight loss %;excess weight loss%;fasting plasma glucose;Glycosylated hemoglobin;oral glucose tolerance test;fasting insulin;Lipid analysis;Body composition analysis;fasting C-peptide;

Countries

China

Contacts

Public ContactXin Huang
huangxinsdu@163.com+86 18560084063

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026