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Esmketamine combined with propofol for anesthesia induction in gastrointestinal surgery: a prospective, randomized, controlled trial

Esmketamine combined with propofol for anesthesia induction in gastrointestinal surgery: a prospective, randomized, controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060641
Enrollment
Unknown
Registered
2022-06-06
Start date
2022-05-31
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia for patients undergoing gastrointestinal surgery

Interventions

group S:inject saline
group K:inject Esketamine

Sponsors

The First People’s Hospital of Foshan
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ASA class I-II; 2. Age in 18-75 years old; 3. Scheduled gastrointestinal tumor surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. History of mental disease and brain disease; 2. Contraindication and allergy of test drug; 3. History of drug abuse; 4. Hypertension in grade III; 5. Patients with severe heart, liver and lung diseases; 6. Who refused to participate in the study.

Design outcomes

Primary

MeasureTime frame
Incidence of hemodynamic instability during anesthesia induction;

Secondary

MeasureTime frame
CO;Blood presure;HR;Dosage of narcotic drugs during anesthesia induction;Dosage of vasoactive drugs during anesthesia induction;Operation time;Wake-up time;Extubation time;PACU residence time;Agitation score in PACU;Delirium score during anesthesia Awakening;Postoperative pain;Side effects;

Contacts

Public ContactWang Hanbing

The First People's Hospital of Foshan

hejian2011@126.com+86 18038865078

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026