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Role of calcium binding protein S100A12 in diagnosis and prognosis of Kawasaki disease

Role of calcium binding protein S100A12 in diagnosis and prognosis of Kawasaki disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060635
Enrollment
Unknown
Registered
2022-06-06
Start date
2022-05-31
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kawasaki disease

Interventions

Control group :None

Sponsors

Jingzhou first people's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 14 Years

Inclusion criteria

Inclusion criteria: All children with Kawasaki disease meet the diagnostic criteria of Kawasaki disease revised by the American Heart Association in 2017: if the duration of onset (39 ~ 40 ?) is more than 5 days and there are more than 4 of the following 5 clinical manifestations, they can be diagnosed as Kawasaki disease. 1. Changes of limbs: erythema of palms and soles in acute stage, hard edema of hands and feet, membranous peeling of finger (toe) end in recovery stage; 2. Pleomorphic rash; 3. Bilateral conjunctival hyperemia; 4. The lips are congested and chapped, the oral mucosa is diffusely congested, and the tongue papilla is prominent, showing a strawberry tongue; 5. Cervical lymph node enlargement. If the duration of fever (39 ~ 40 ?) is more than 5 days, 4 of the above 5 clinical manifestations are not met, but the results of color Doppler echocardiography show coronary artery dilatation.

Exclusion criteria

Exclusion criteria: Febrile diseases such as scarlet fever, drug allergy syndrome, Stevens Johnson syndrome, toxic shock syndrome, adenovirus infection and Epstein Barr (EB) virus infection were excluded

Design outcomes

Primary

MeasureTime frame
S100A12;

Countries

China

Contacts

Public ContactPan Yan

Jingzhou first people's Hospital, 8 Hangkong Road, Shashi District, Jingzhou, Hubei

woshipanyan@126.com+86 18163139706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026