Chronic kidney disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) 18-65 years old; (2) CKD4-5 or CKD1-3 with hypertension; (3) 24-hour urinary sodium excretion > 130mmol/d; (4) Self-care (Bathel score > 60); (5) Normal intelligence (MMSE score >=24) (6) Proficient in the use of mobile apps; (7) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Rapid and persistent decline in eGFR (AKI); (2) Kidney transplantation within 1 year; (3) cardiovascular events occurred within 6 months; (4) Systolic blood pressure >160 mmHg or diastolic blood pressure >100 MMHG; (5) Have participated in similar studies before; (6) Other medical conditions may interfere with the completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sodium urine 24 hours;Blood pressure (systolic/diastolic);Incidence of renal end-point events: including ESKD and renal replacement therapy (hemodialysis, peritoneal dialysis, and kidney transplantation);Rate of renal function progression: the slope of change in glomerular filtration rate (eGFR) before and after intervention;; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30 days unplanned readmission;60 days unplanned readmission;30 days of unplanned all-cause death;60 days of unplanned all-cause death;Cardiovascular and cerebrovascular events (including myocardial infarction, coronary heart disease, angina pectoris, arrhythmia, heart failure, cardiac arrest, death from cerebrovascular events, etc.);Urine protein quantification: random urine protein/creatinine ratio / 24-hour urine protein quantification; | — |
Countries
China
Contacts
Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing