Bariatric Surgeries
Conditions
Interventions
S-Ketamine : S-Ketamine Infusion
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years; 2. ASA ?-III grade; 3. BMI >= 30 kg/?; 4. Patients undergoing Laparoscopic Bariatric Surgery ; 5. The patient or family member fully understood the purpose and significance of this experiment, volunteered to participate in this clinical trial, and signed informed consent
Exclusion criteria
Exclusion criteria: 1. Drug allergy and contraindications to S-ketamine; (Patients at serious risk of hypertension or elevated intracranial pressure;??Patients with poorly controlled or untreated hypertension; Glaucoma; An untreated or undertreated patient with hyperthyroidism; 2. Complicated with serious cardiovascular, kidney disease, liver disease; 3. Have taken antidepressants or received other interventions in the past 4 weeks; 4. Patients with moderate or above anemia (hemoglobin < 90 g/L); 5. Long-term use of sedatives, analgesics, long-term alcoholism; 6. Inability to understand cooperation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR40; | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time;Eye-opening time;Time during PACU;Peak pain in PACU;Hemodynamic changes;postoperative complications in PACU;Intraoperative opioid use;Intraoperative propofol dosage;Postoperative analgesic drug use;Postoperative pain;BIS;QoR40;Time to Aldrete’s score 9; | — |
Countries
China
Contacts
Public ContactZhiping Wang
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed