Respiratory failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients requiring invasive mechanical ventilation with an expected duration of mechanical ventilation of at least 48 hours; 2. Adult patients (>=18 years old) of any gender; 3. Patients who agree to participate in this trial and sign the "Informed Consent Form".
Exclusion criteria
Exclusion criteria: 1. Patients who are participating in other clinical trials; 2. Pregnant women; 3. Diseases leading to uncontrollable primary respiratory failure, such as patients with central respiratory failure, patients with respiratory failure due to neuromuscular disease (including High-level cervical spine injury), patients with end-stage cardiopulmonary failure, etc; 4. Patients with large lobe atelectasis, spontaneous pneumothorax, acute pulmonary embolism, cervical medullary injury and peripheral neuropathy; 5. Patients who are hemodynamically unstable and require high-dose vasoactive drugs; 6. Patients deemed unsuitable by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tidal volume;Blood oxygen saturation;End expiratory carbon dioxide partial pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure;Minute ventilation; | — |
Countries
China
Contacts
Shenzhen Second People's Hospital