Spinal cord injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Vital signs are stable and able to complete the training; 2. Age: 18-75 years old, gender is not limited; 3. Traumatic spinal cord injury (including surgical trauma) confirmed by CT or MRI in line with the International Diagnostic Criteria for Neurological Classification of Spinal Cord Injury revised by the American Spinal Cord Injury Society in 2019; 4. The motor plane of spinal nerve injury is T2-T12, AIS spinal cord injury grades A, B, and C; 5. The course of the disease is more than 3 months and less than 2 years; 6. Good cognitive function, MMSE >= 24 points, can understand and actively participate in the training program, agree and sign the informed consent form for this clinical study.
Exclusion criteria
Exclusion criteria: 1. Complications that limit the patient's ability to exercise lower extremity deep vein thrombosis, diabetes, hypertension, coronary heart disease, severe osteoporosis, and female pregnancy; 2. Patients with metabolic bone disease, diabetes, thyroid and parathyroid disease, autoimmune disease, severe liver and kidney disease, malignant tumor and the use of drugs that affect bone metabolism; 3. Menopausal female patients; 4. Patients with early knee fracture, knee arthritis or severe knee pain; 5. The patient has severe orthostatic hypotension when standing 6. The investigator judges that the patient has poor compliance or does not understand the test, and cannot complete the study as required; 7. Participated in other drugs or clinical trials during the same period; 8. Other circumstances that the investigator judges not suitable for inclusion or the patient cannot tolerate the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone density;Extremity surface electromyography assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensory score;Lower extremity motor score;Modified Ashworth Classification; | — |
Countries
China
Contacts
Jiangsu Provincial People's Hospital