Skip to content

Probiotic-related Zeger therapy promoting periodontal microecological homeostasis in healthy adults: a clinical randomized controlled trial

Probiotic therapy promoting periodontal microecological homeostasis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060555
Enrollment
Unknown
Registered
2022-06-04
Start date
2022-05-28
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

Group 1:Koumiss

Sponsors

West China Stomatological Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. 18-35 years old; 2. No alveolar bone resorption was observed on the X-ray film at baseline; 3. Gingival index (GI) > 0 at baseline; 4. In good general health; 5. More than 20 natural teeth (excluding third molars).

Exclusion criteria

Exclusion criteria: 1. Severe systemic and hematological diseases; 2. Pregnancy or breastfeeding; 3. Physical or mental disorders that may affect oral health behavior; 4. History of dairy allergy; 5. Use of non-steroidal or steroidal anti-inflammatory drugs, analgesics or antibiotics in the 4 weeks prior to the study; 6. Ongoing orthodontic treatment (including wearing orthodontics) and other unfinished dental treatment; 7. Acute oral lesions.

Design outcomes

Primary

MeasureTime frame
Gingival bleeding index;High-throughput sequencing results of plaque microbes;

Secondary

MeasureTime frame
Gingival index;Plaque index;Probing depth;

Countries

China

Contacts

Public ContactWei Yin

West China Stomatological Hospital, Sichuan University

yinwei1980@scu.edu.cn+86 13882208058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026