Periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 18-35 years old; 2. No alveolar bone resorption was observed on the X-ray film at baseline; 3. Gingival index (GI) > 0 at baseline; 4. In good general health; 5. More than 20 natural teeth (excluding third molars).
Exclusion criteria
Exclusion criteria: 1. Severe systemic and hematological diseases; 2. Pregnancy or breastfeeding; 3. Physical or mental disorders that may affect oral health behavior; 4. History of dairy allergy; 5. Use of non-steroidal or steroidal anti-inflammatory drugs, analgesics or antibiotics in the 4 weeks prior to the study; 6. Ongoing orthodontic treatment (including wearing orthodontics) and other unfinished dental treatment; 7. Acute oral lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival bleeding index;High-throughput sequencing results of plaque microbes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival index;Plaque index;Probing depth; | — |
Countries
China
Contacts
West China Stomatological Hospital, Sichuan University