Application of regional nerve block combined with intravenous sedation in perineal surgery

Application of perineal block technique combined with remazolam in perineal prostate biopsy in elderly patients under day surgery mode

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200060554

Enrollment

Unknown

Registered

2022-06-04

Start date

2022-05-28

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer

Interventions

Group NB:Combined pudendal and periprostatic nerve block technique combined with intravenous pumping remazolam for sedation

Group CON:All intravenous anesthesia with propofol and remifentanil

Eligibility

Sex/Gender

Male

Age

65 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1. Preoperative ultrasonography suggested space occupying lesions in prostate; 2. BMI<=27.00kg/m2.

Exclusion criteria

Exclusion criteria: 1. Patients with coagulopathy, infection at puncture site, allergy to ropivacaine, severe hypertension of grade 2 or above, myocardial ischemic disease, and inability to understand VAS score.

Design outcomes

Primary

Measure	Time frame
Visual analog scale, VAS;Pittsburgh sleep quality index, PSQI;Digit Symbol Substitution Test (DSST);Number connection test, NCT;	—

Secondary

Measure	Time frame
Heart rate;Mean arterial pressure;	—

Countries

China

Contacts

Public ContactYan Lijuan

First Affiliated Hospital of Xiamen University

yanlijuan0122@126.com+86 15710668779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026