Early gastrointestinal cancer
Conditions
Interventions
Gold Standard:Pathological diagnosis
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18~80 years old, no gender restrictions, women are not during pregnancy and lactation; 2. Endoscopy and/or colonoscopy are acceptable; 3. The enrolled patients are newly diagnosed patients and have not received surgery, radiotherapy, chemotherapy, targeted therapy, or other tumor-related interventions; 4. Stop anticoagulant drugs such as warfarin, aspirin, and Plavix for 1 week, and stop low molecular weight heparin on the same day; 5. No history of other tumor diseases, normal liver and kidney function; 6. No major trauma requiring blood transfusion occurred within one week.
Exclusion criteria
Exclusion criteria: 1. Previously suffered from esophageal cancer, gastric cancer, intestinal cancer, and digestive tract adenoma; 2. Have a history of other cancers; 3. Systemic inflammatory response syndrome; 4. Previously experienced esophageal, gastric, or colorectal adenoma removal or tumor resection; 5. Patients with Lynch syndrome in the family; 6. History of severe cardiovascular disease (such as the previous history of myocardial infarction, coronary artery bypass grafting or coronary stenting; history of congestive heart failure; myocardial infarction within 6 months, uncontrolled severe hypertension, etc.) and the investigators determine that they are not suitable for enrollment; 7. Participated in an "interventional" clinical trial within the past 30 days and took the trial drug; 8. Patients with other diseases who were judged by the investigator to be unsuitable for inclusion; 9. Failure to follow the test plan to collect blood on time; 10. The blood samples failed to meet the requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DNA methylation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathological diagnosis; | — |
Countries
China
Contacts
Public ContactZhong Yunshi
Zhongshan Hospital, Fudan University
Outcome results
None listed