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The clinical study of geometric localization technique based on CT measurement for peripheral pulmonary GGO in sublobar resection

A prospective, randomized and comparative study of geometric localization technique based on CT measurement and CT-guided percutaneaous marking technique for peripheral GGO during wedge resection

Status
Recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060527
Enrollment
Unknown
Registered
2022-06-04
Start date
2022-05-25
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary GGO nodules

Interventions

GLT group:Using geometric localization technique based on CT measurement
CGPM group:Using CT-guided percutaneaous marking technique

Sponsors

The First Affiliated Hospital of Chongqing Medical Universit
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Solitary pulmonary GGO nodule, the maximum diameter is less than 20mm and Consolidation/tumor ratio (C/T) = 20mm or C/T >=0.25; 3. Located at the outer third of the lung parenchyma; 4. Suspicious-appearing malignancy or at least 3 months follow up for not confirmed lesion or biopsy-proven malignancies, and no lymph nodes metastasis was indicated by CT (cN0); 5. The lesion does not invade visceral pleaura; 6. The patients will receive wedge resection and sufficient resection margin can be guaranteed according to preoperative CT.

Exclusion criteria

Exclusion criteria: 1. Patients were suffering from severe comorbidities that can not be tolerable for surgery, such as pulmonary diseases, heart diseases, liver and renal diseases or cerebral diseases; 2. Patients have contraindication for puncture for CT-guided percutaneous marking technique, such as cutaneaous infection; or the patients do not fit for CT-guided percutaneous marking technique; 3. Other positioning methods are used; 4. Patients are not willing to participate in this study.

Design outcomes

Primary

MeasureTime frame
Successful localization rate;

Secondary

MeasureTime frame
Sufficient resection margin rate;Localization related complication rate;The distance between nodule and marked/punctured visceral pleura point;Time for localization;Time for operation;In-hospital cost;

Countries

China

Contacts

Public ContactMengjun Bie

The First Affiliated Hospital of Chongqing Medical University

513193406@qq.com+86 15696014696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026