General anesthesia
Conditions
Interventions
High concentration:Change the concentration of remifentanil
Middle concentration:Change the concentration of remifentanil
Low concentration:Change the concentration of remifentanil
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status I or II; 2. All patients' age range is between 30 and 65; 3. Bbody mass index (BMI) is between 18.5 and 29.5 kg/m2.
Exclusion criteria
Exclusion criteria: 1. Poor compliance or non-cooperate; 2. Presence of serious disease (cardiovascular disease, bronchial asthma, uncontrolled severe hypertension, fearful blood system dysfunction, liver or kidney dysfunction, obvious electrolyte abnormalities); 3. Second-degree atrioventricular block, bradycardia (HR< 50 bpm), low blood pressure (SBP< 90 mmHg); 4. History of neurological disease, chronic pain, drug addiction and alcoholism, long-term opioid use; 5. History of allergy to opioids; 6. Slow intestinal peristalsis or intestinal obstruction; 7. Participant in clinical trials involving other drugs within four weeks; 8. The presence of other conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient state index;Concentration of remifentanil;Number of times to handle the depth of anesthesia intraoperative;Extubation time after surgery; | — |
Countries
China
Contacts
Public ContactSheng Wang
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed