Postoperative Cognitive Dysfunction
Conditions
Interventions
intervention group:Computerized cognition training
Control group:Tablet computer based basic training
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Agree to participate in this study voluntarily; 2. Age >= 60 years old; 3. Patients who intend to accept elective coronary artery bypass grafting or valve replacement; 4. The preoperative hospital stay is expected to be 5 days or more.
Exclusion criteria
Exclusion criteria: 1. Definite diagnosis of senile dementia and MOCA score <= 18; 2. Patients with severe visual or hearing impairment who cannot complete the cognitive function assessment; 3. Patients with limb movement disorder who cannot complete the cognitive function assessment; 4. Patients with claustrophobia who cannot complete fMRI examination; 5. The expected survival time is less than 1 month; 6. Patients who are accepting other operations, such as tumor resection; 7. Patients within 3 months or participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative 7-day cognitive dysfunction ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative 7-day changes of cognitive scores;Postoperative 7-day changes of cortical network connectivity function;Postoperative 7-day changes of sleep quality;Incidence of postoperative delirium within 7 days;Incidence of postoperative 30-day cognitive dysfunction;Postoperative 30-day main complications and mortality; | — |
Countries
China
Contacts
Public ContactDongliang Mu
Peking University First Hospital
Outcome results
None listed