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Effect of nebulized inhalation of tetracaine surface anesthesia on the dosage of general anesthesia and pharynx after laryngopharyngeal surgery

Effect of nebulized inhalation of tetracaine surface anesthesia on the dosage of general anesthesia and pharynx after laryngopharyngeal surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060509
Enrollment
Unknown
Registered
2022-06-03
Start date
2022-05-25
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sore throat

Interventions

G group:Each patient in group G is aerosolized with 1% tetracaine 50mg for 15 minutes before surgery
D group:Each patient in group D is aerosolized with 0.9% normal saline for 15 minutes before surgery

Sponsors

Affiliated Hospital of Yan'an University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA grade I~II. 2. Age 18~65 years old, BMI 18~28Kg/m2; 3. The operation time was less than 2 hours; 4. No history of sore throat before operation; 5. Patients without severe hypertension and cardiac cerebrovascular disease.

Exclusion criteria

Exclusion criteria: 1. Uncooperative patient; 2. Difficult airway patients; 3. Allergic to ester anesthetics.

Design outcomes

Primary

MeasureTime frame
Dosage of propofol, remifentanil and Rocuronium in general anesthesia;The incidence of pharyngeal pain (VAS score) was observed within 24 hours after operation;

Secondary

MeasureTime frame
The degree of pain;The duration of the pain;Blood pressure;Heart rate;Mean arterial pressure;

Countries

China

Contacts

Public ContactYanbin Bai

Affiliated Hospital of Yan'an University

1719148711@qq.com+86 15591153360

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026