Skip to content

Clinical intervention study on OSF (oral submucosal fibrosis) caused by chewing betel nut

Clinical intervention study on OSF (oral submucosal fibrosis) caused by chewing betel nut

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060497
Enrollment
Unknown
Registered
2022-06-03
Start date
2022-05-23
Completion date
Unknown
Last updated
2023-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral submucosal fibrosis (OSF)

Interventions

control group:Triamcinolone acetonide injection therapy
experimental group 1:Injection + smear drug treatment
experimental group 2:Salvia paste + growth factor gel treatment

Sponsors

Xiangya Stomatological Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged above 18 years; 2. No gender limit; 3. Agree not to use other therapeutic drugs during the treatment period; 4. The patient is conscious, has no communication barriers, and can answer questions correctly; 5. Voluntarily participate in this intervention experiment and sign informed consent, which mainly includes informed consent to the disease detection method and treatment plan.

Exclusion criteria

Exclusion criteria: 1. Patients with OSF who received other treatments within three months; 2. Associated with other systemic immune diseases; 3. Allergic to salvia miltiorrhiza, triamcinolone, curcumin and epidermal growth factor; 4. Participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
mouth opening;mucosal burning discomfort;mucous membrane color;

Countries

China

Contacts

Public ContactTang Zhan'gui

Xiangya Stomatological Hospital of Central South University

zhgtang@csu.edu.cn+86 13907317983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026