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Genetic differences in families and the pathogenesis of Alzheimer's disease

Genetic differences in families and the pathogenesis of Alzheimer's disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060485
Enrollment
Unknown
Registered
2022-06-03
Start date
2022-06-15
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease (AD)

Interventions

case series:None

Sponsors

Affiliated Hospital of Zunyi Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. The first observer was a 65-80 year old female patient. The first observer in the observation group was diagnosed with Alzheimer's disease, while the first observer in the control group was diagnosed without Alzheimer's disease; 2. The second observer was a 65-80 year old female, a sister of the first observer, who did not suffer from Alzheimer's disease; 3. The third observer is a woman aged 40-60 years, who is the biological daughter of the first observer. All observers with civil capacity know about this research project, and their entrusted agents without civil capacity know about this project.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of serious mental illness; 2. Clearly diagnose patients with neurological diseases; 3. Patients with severe circulatory diseases and their treatment; 4. Patients with a history of major surgery or trauma; 5. Patients with dysfunction of important organs; 6. Patients with severe endocrine system diseases; 7. Patients who cannot cooperate with the inspection; 8. The researchers did not consider it suitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Intelligence Scale;Genome;

Countries

China

Contacts

Public ContactZhu Yuhang

Affiliated Hospital of Zunyi Medical University, Guizhou University

zhuyuhang_zmc@sina.com+86 15885605300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026